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Clinical
Calculate serum osmolality from sodium, glucose, and BUN. Normal range: 275–295 mOsm/kg. Osmolal gap >10 suggests toxic alcohol ingestion (methanol, ethylene glycol, isopropanol) or other unmeasured osmoles.
Formula
Osmolality = 2×Na + Glucose/18 + BUN/2.8
Inputs
Clinical
Calculate the anion gap and albumin-corrected anion gap to help evaluate metabolic acidosis. Essential for the ER and ICU workup.
Formula
AG = Na⁺ − (Cl⁻ + HCO₃⁻); Corrected AG = AG + 2.5 × (4.0 − Albumin)
Inputs