Printed on 2/13/2026
For informational purposes only. This is not medical advice.
Creatinine clearance (CrCl) estimates how quickly the kidneys filter creatinine from the blood. The Cockcroft-Gault equation, published in 1976, remains the most widely used formula for renal drug dosing adjustments. Many medication guidelines and drug labels reference CrCl calculated by this equation when recommending dose modifications for patients with impaired kidney function.
Formula: CrCl = [(140 − age) × weight] / (72 × Scr) × 0.85 if female
Disclaimer: This tool is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about your health.
Calculate estimated glomerular filtration rate (eGFR) using the CKD-EPI 2021 equation. Assess kidney function and CKD staging from serum creatinine.
Body MetricsCalculate your body surface area using Du Bois, Mosteller, and Haycock formulas. BSA is used in clinical medicine for drug dosing and medical calculations.
Creatinine clearance (CrCl) estimates the volume of blood plasma that is cleared of creatinine per minute by the kidneys. It is expressed in mL/min and serves as a proxy for kidney filtration ability. It is primarily used to guide drug dosing in patients with reduced kidney function.
Cockcroft-Gault estimates creatinine clearance (not GFR) and includes body weight, making it useful for drug dosing. eGFR (CKD-EPI) is normalized to body surface area and is used for CKD staging. Many drug labels specify Cockcroft-Gault CrCl for dose adjustments, which is why both calculators are valuable.
Normal CrCl is approximately 90–140 mL/min for men and 80–125 mL/min for women. Values decrease with age. CrCl below 60 mL/min generally indicates significant kidney impairment and many drugs require dose adjustments at this level or below.
For most patients, actual body weight is used. However, in obese patients (>30% above ideal body weight), some clinicians use adjusted body weight. For very underweight patients, actual weight is used. This calculator uses actual body weight as entered.