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Printed on 4/19/2026
For informational purposes only. This is not medical advice.
AIP is calculated as log10(triglycerides/HDL-C) using molar concentrations. It reflects the balance between atherogenic and protective lipoprotein patterns and is associated with cardiovascular risk in multiple observational studies.
Formula: AIP = log10((TG [mmol/L]) / (HDL-C [mmol/L]))
AIP summarizes the triglyceride-to-HDL relationship on a logarithmic scale. Higher values suggest a more atherogenic lipid phenotype and may indicate increased residual cardiovascular risk.
Use AIP as an adjunctive lipid-risk marker in patients with mixed dyslipidemia, metabolic syndrome traits, or discordant traditional lipid markers.
AIP is not currently the primary treatment target in major lipid guidelines. It should be interpreted as a supplementary marker alongside standard lipid and clinical risk metrics.
For related assessments, see Cholesterol Ratio, LDL Calculator and ASCVD Risk Calculator.
Disclaimer: This tool is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about your health.
Calculate total cholesterol/HDL ratio and triglyceride/HDL ratio from a standard lipid panel. A total/HDL ratio below 3.5 is optimal. For full cardiovascular risk assessment, use [ASCVD Risk Calculator](/tools/ascvd-risk) or [Framingham Risk Score](/tools/framingham-risk).
CardiologyCalculate LDL cholesterol from total cholesterol, HDL, and triglycerides using the Friedewald equation. Also reports non-HDL and total/HDL ratio.
CardiologyCalculate 10-year ASCVD risk using current 2026 ACC/AHA Pooled Cohort Equations. Statin thresholds: <5% low, 5–7.5% borderline, ≥7.5% intermediate, ≥20% high.