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Printed on 4/19/2026
For informational purposes only. This is not medical advice.
The ISTH DIC score combines platelet count, D-dimer/fibrin markers, prothrombin time prolongation, and fibrinogen level to help identify overt DIC in appropriate clinical contexts such as sepsis, trauma, or malignancy.
Formula: ISTH DIC score = platelet points + fibrin marker points + PT prolongation points + fibrinogen points. Overt DIC if total >=5.
Higher scores indicate greater likelihood of overt DIC when combined with an underlying clinical condition known to trigger systemic coagulation activation.
Use this score in suspected DIC contexts such as sepsis, trauma, obstetric emergencies, or advanced malignancy with coagulation abnormalities.
Lab thresholds and fibrin-marker interpretation vary by institution. This score must be interpreted with clinical context and serial trends.
For related assessments, see 4T Score (HIT), SOFA Score and qSOFA Score.
Disclaimer: This tool is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about your health.
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