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Printed on 4/19/2026
For informational purposes only. This is not medical advice.
FIB-4 is a non-invasive fibrosis risk score widely used in chronic liver disease triage, including NAFLD and viral hepatitis pathways. It helps identify low-risk patients versus those needing elastography or specialist evaluation.
Formula: FIB-4 = (Age x AST) / (Platelets x sqrt(ALT)).
Lower FIB-4 values suggest lower probability of advanced fibrosis, while higher values indicate greater risk and need for further evaluation.
Use FIB-4 for non-invasive fibrosis risk stratification in chronic liver disease pathways and primary care-to-hepatology triage.
FIB-4 can be confounded by acute transaminase elevations, age effects, and non-hepatic platelet abnormalities. It should not replace definitive fibrosis assessment when clinically indicated.
For related assessments, see MELD Score, Child-Pugh Score and AST/ALT Ratio.
Disclaimer: This tool is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about your health.
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