Q: How is lupus disease activity measured?

SLEDAI-2K is the standard tool, scoring 24 weighted clinical and laboratory descriptors — from neuropsychiatric findings to renal, mucocutaneous, and immunologic markers — present within the prior 10 days, summed into a single activity score used to detect flares and guide immunosuppression.

Q: How is rheumatoid arthritis formally classified?

The 2010 ACR/EULAR criteria score joint involvement, serology (RF/ACPA), acute-phase reactants (CRP/ESR), and symptom duration, with a threshold of 6 out of 10 points classifying definite RA in a patient with synovitis not better explained by another disease.

Question 1

What is DAS28 used for?

Accepted Answer

DAS28 measures rheumatoid arthritis disease activity by combining tender and swollen joint counts, an inflammatory marker (ESR or CRP), and patient global health into one score. It drives treat-to-target decisions: remission is <2.6, and scores above 5.1 indicate high disease activity warranting treatment escalation.

Question 2

How is lupus disease activity measured?

Accepted Answer

SLEDAI-2K is the standard tool, scoring 24 weighted clinical and laboratory descriptors — from neuropsychiatric findings to renal, mucocutaneous, and immunologic markers — present within the prior 10 days, summed into a single activity score used to detect flares and guide immunosuppression.

Question 3

How is rheumatoid arthritis formally classified?

Accepted Answer

The 2010 ACR/EULAR criteria score joint involvement, serology (RF/ACPA), acute-phase reactants (CRP/ESR), and symptom duration, with a threshold of 6 out of 10 points classifying definite RA in a patient with synovitis not better explained by another disease.

Rheumatology Calculators & Classification Criteria

All Rheumatology Tools (4)

DAS28 Score

SLEDAI-2K

RA Classification (ACR/EULAR)

Gout Criteria (ACR/EULAR)

Frequently Asked Questions